Talk to your doctor about PALSONIFY with confidence
Whether you’re managing acromegaly with injections, restarting treatment after time off, or have never been on treatment, PALSONIFY helps control IGF-1 levels and symptoms.*
In clinical studies, most PALSONIFY side effects were mild to moderate, stomach related, and generally didn’t require stopping treatment.
Build your personalized discussion guide to help start a conversation with your healthcare provider about whether PALSONIFY is right for you.
*PALSONIFY maintained or lowered IGF-1 and reduced the severity of common acromegaly symptoms in most patients in clinical studies.
IGF-1=insulin-like growth factor 1.
This is not a screening or diagnostic tool but is meant to gather your symptoms to discuss with your healthcare provider.
Where are you in your treatment journey?
- Step 1
- Step 2
- Step 3
Choose the statement below that best describes you.
This is not a screening or diagnostic tool but is meant to gather your symptoms to discuss with your healthcare provider.
What are your treatment goals?
- Step 1
- Step 2
- Step 3
Select all that apply.
This is not a screening or diagnostic tool but is meant to gather your symptoms to discuss with your healthcare provider.
How are you currently feeling?
- Step 1
- Step 2
- Step 3
Your lGF-1 level is important but so is how you feel. Understanding your symptoms and how they impact your life could lead to a more specific conversation with your healthcare provider about your treatment needs.
Select the acromegaly symptoms you would like to talk to your doctor about.
This is not a screening or diagnostic tool but is meant to gather your symptoms to discuss with your healthcare provider.
Here is your personalized discussion guide:
STEP 1: Where are you in your treatment journey?
I’m currently on treatment.
STEP 2: What are your treatment goals?
I’m currently on treatment.
Use these questions to ask your doctor about your IGF-1 level:
- “Can we review my IGF-1 levels and what they mean?”
- “What should my goal IGF-1 level be?”
- “Even with a normal IGF-1 level, I still have symptoms. What does that mean?”
- “If I’m not managing both my IGF-1 and my symptoms, am I truly controlled?”
STEP 3: How are you currently feeling?
Look at the list of symptoms you have chosen…
Look at the list of symptoms you have chosen…
Remember, symptoms have more than just a physical impact. Don’t forget to bring up how they affect other parts of your life and the lives of those who care about you.
- Are you missing work because of your acromegaly?
- Are you canceling or avoiding social activities?
- Do they influence your emotional and mental health?
- Is acromegaly impacting your family and others who care about you?
STEP 4: Is PALSONIFY the right treatment option for you?
Only you and your doctor know what the best treatment plan is for your acromegaly. Here are some discussion points to consider that may help you feel more confident in making a decision about PALSONIFY.
Quick questions to get the conversation started.
Since you’re currently on treatment, try these:
- “How do we define true acromegaly control?”
- “What should my goal IGF-1 level be?”
- “Will my acromegaly stay controlled if I switch treatments?”
- “What should I expect during the transition to PALSONIFY?”
- “What steps do I need to take to get started on PALSONIFY?”
Since you’re not on treatment, try these:
- “How do we define true acromegaly control?”
- “What should my goal IGF-1 level be?”
- “How does PALSONIFY help people like me who aren’t on medication?”
- “When can I expect to see results if I start on PALSONIFY?”
- “What steps do I need to take to get started on PALSONIFY?”
STEP 5: Have you prepared for your visit?
Here are some tips to help you get the most out of your next appointment
If you’re having trouble scheduling an in-person visit, consider telemedicine options to connect with a healthcare provider virtually.
If you currently aren’t seeing a doctor for your acromegaly, visit CrinetiCARE® to find one near you. Once you’ve chosen a healthcare provider, consider telemedicine options to connect with them virtually if you’re having trouble scheduling an in-person visit.
Your previsit checklist:
- Write down your top questions and your treatment goals
- Bring any notes you’ve taken about your symptoms
- Ask about support and copay programs to help you get started on PALSONIFY
Remember, your experiences with acromegaly are valid. If your IGF-1 level is considered “normal” but you’re still struggling with symptoms, it’s important you speak up. If you’ve been frustrated by the disruptions of monthly injections in the past, you deserve to find a treatment that works for your life.
CrinetiCARE® is here to support you—every step of the way
CrinetiCARE provides personalized support to help you navigate your treatment journey with PALSONIFY. Whether you have questions about insurance coverage, need help finding a healthcare provider, or are seeking a nurse educator, CrinetiCARE is here to help.
- 844-CRN-HELP (844-276-4357)
- 844-CRN-FAXX (844-276-3299)
- Visit CrinetiCARE.com
Before your visit, consider printing or saving your selections and questions to bring with you.
Here is your personalized discussion guide:
STEP 1: Where are you in your treatment journey?
I’m currently on treatment.
STEP 2: What are your treatment goals?
- Managing my symptoms
- Lowering my IGF-1 level
- Simplifying my treatment routine
- Reducing breakthrough symptoms
- Other
Use these questions to ask your doctor about your IGF-1 level:
- “Can we review my IGF-1 levels and what they mean?”
- “What should my goal IGF-1 level be?”
- “Even with a normal IGF-1 level, I still have symptoms. What does that mean?”
- “If I’m not managing both my IGF-1 and my symptoms, am I truly controlled?”
These things matter, too.
STEP 3: How are you currently feeling?
Look at the list of symptoms you have chosen…
- Headache
- Joint pain
- Sweating
- Tiredness
- Short-term memory difficulties
- Other
Remember, symptoms have more than just a physical impact. Don’t forget to bring up how they affect other parts of your life and the lives of those who care about you.
- Are you missing work because of your acromegaly?
- Are you canceling or avoiding social activities?
- Do they influence your emotional and mental health?
- Is acromegaly impacting your family and others who care about you?
These things matter, too.
STEP 4: Is PALSONIFY the right treatment option for you?
Only you and your doctor know what the best treatment plan is for your acromegaly. Here are some discussion points to consider that may help you feel more confident in making a decision about PALSONIFY.
Quick questions to get the conversation started.
Since you’re currently on treatment, try these:
- “How do we define true acromegaly control?”
- “What should my goal IGF-1 level be?”
- “Will my acromegaly stay controlled if I switch treatments?”
- “What should I expect during the transition to PALSONIFY?”
- “What steps do I need to take to get started on PALSONIFY?”
Since you’re not on treatment, try these:
- “How do we define true acromegaly control?”
- “What should my goal IGF-1 level be?”
- “How does PALSONIFY help people like me who aren’t on medication?”
- “When can I expect to see results if I start on PALSONIFY?”
- “What steps do I need to take to get started on PALSONIFY?”
STEP 5: Have you prepared for your visit?
Here are some tips to help you get the most out of your next appointment.
If you’re having trouble scheduling an in-person visit, consider telemedicine options to connect with a healthcare provider virtually.
If you currently aren’t seeing a doctor for your acromegaly, visit CrinetiCARE® to find one near you. Once you’ve chosen a healthcare provider, consider telemedicine options to connect with them virtually if you’re having trouble scheduling an in-person visit.
Your previsit checklist:
- Write down your top questions and your treatment goals
- Bring any notes you’ve taken about your symptoms
- Ask about support and copay programs to help you get started on PALSONIFY
What is PALSONIFY?
- PALSONIFY is a prescription medicine used to treat adults with acromegaly for whom surgery was not effective or surgery is not an option
- It is not known if PALSONIFY is safe and effective in children
IMPORTANT SAFETY INFORMATION
What should I tell my healthcare provider before taking PALSONIFY? Before taking PALSONIFY, tell your healthcare provider about all your medical conditions, including if you:- have gallbladder problems
- have blood sugar control problems (low blood sugar or high blood sugar)
- have problems with low heart rate
- are pregnant or plan to become pregnant. It is not known if PALSONIFY will harm your unborn baby.
- are breastfeeding or plan to breastfeed. It is not known if PALSONIFY passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby if you take PALSONIFY.
- Gallbladder problems: PALSONIFY may cause problems with the gallbladder. Tell your healthcare provider if you have sudden pain in the upper right area of your stomach (abdomen), sudden pain in your right shoulder or between your shoulder blades, yellowing of your skin or the whites of your eyes, or pale stools.
- Blood sugar problems: PALSONIFY may change hormone levels, potentially causing either high blood sugar (hyperglycemia), including diabetes, or low blood sugar (hypoglycemia). Tell your healthcare provider if you have problems with high or low blood sugar. Your healthcare provider will check your blood sugar when you start taking PALSONIFY or when your dose is changed.
- Heart rate problems: Tell your healthcare provider if your heart is not beating normally.
- Thyroid problems: PALSONIFY may keep your thyroid from releasing thyroid hormones, leading to hypothyroidism. Your thyroid function may be checked periodically during your treatment with PALSONIFY.
- Fatty stools: PALSONIFY may cause your body to have problems with absorbing dietary fats. Tell your healthcare provider if you have any new or worsening symptoms, including fatty stools, changes in the color of your stools, loose stools, stomach (abdominal) bloating, or weight loss.
- Low vitamin B12 levels in your blood: Your healthcare provider may check your vitamin B12 levels during treatment with PALSONIFY.
What is PALSONIFY?
- PALSONIFY is a prescription medicine used to treat adults with acromegaly for whom surgery was not effective or surgery is not an option
- It is not known if PALSONIFY is safe and effective in children
IMPORTANT SAFETY INFORMATION
What should I tell my healthcare provider before taking PALSONIFY?
Before taking PALSONIFY, tell your healthcare provider about all your medical conditions, including if you:
- have gallbladder problems
- have blood sugar control problems (low blood sugar or high blood sugar)
- have problems with low heart rate
- are pregnant or plan to become pregnant. It is not known if PALSONIFY will harm your unborn baby.
- are breastfeeding or plan to breastfeed. It is not known if PALSONIFY passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby if you take PALSONIFY.
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. PALSONIFY may affect the way other medicines work, and other medicines may affect how PALSONIFY works.
Especially tell your healthcare provider if you take any medicines that can slow the heart rate.
Know the medicines you take. Keep a list of them to show your healthcare provider and pharmacist when you get a new medicine.
What are the possible side effects of PALSONIFY?
PALSONIFY may cause serious side effects including:
- Gallbladder problems: PALSONIFY may cause problems with the gallbladder. Tell your healthcare provider if you have sudden pain in the upper right area of your stomach (abdomen), sudden pain in your right shoulder or between your shoulder blades, yellowing of your skin or the whites of your eyes, or pale stools.
- Blood sugar problems: PALSONIFY may change hormone levels, potentially causing either high blood sugar (hyperglycemia), including diabetes, or low blood sugar (hypoglycemia). Tell your healthcare provider if you have problems with high or low blood sugar. Your healthcare provider will check your blood sugar when you start taking PALSONIFY or when your dose is changed.
- Heart rate problems: Tell your healthcare provider if your heart is not beating normally.
- Thyroid problems: PALSONIFY may keep your thyroid from releasing thyroid hormones, leading to hypothyroidism. Your thyroid function may be checked periodically during your treatment with PALSONIFY.
- Fatty stools: PALSONIFY may cause your body to have problems with absorbing dietary fats. Tell your healthcare provider if you have any new or worsening symptoms, including fatty stools, changes in the color of your stools, loose stools, stomach (abdominal) bloating, or weight loss.
- Low vitamin B12 levels in your blood: Your healthcare provider may check your vitamin B12 levels during treatment with PALSONIFY.
The most common side effects of PALSONIFY include diarrhea, pain in your stomach (abdominal) area, nausea and vomiting, decreased appetite, slow heart rate (bradycardia), high blood sugar levels (hyperglycemia), and irregular heartbeat (palpitations).
These are not all the possible side effects of PALSONIFY. For more information, ask your healthcare provider or pharmacist.
You are encouraged to report negative side effects to Crinetics Pharmaceuticals at 1-833-CRN-INFO (1-833-276-4636) or FDA at
1-800-FDA-1088 or www.fda.gov/medwatch.
Please see Full Prescribing Information, including Patient Information, and talk to your doctor.
What is PALSONIFY?
- PALSONIFY is a prescription medicine used to treat adults with acromegaly for whom surgery was not effective or surgery is not an option
- It is not known if PALSONIFY is safe and effective in children
IMPORTANT SAFETY INFORMATION
What should I tell my healthcare provider before taking PALSONIFY?
Before taking PALSONIFY, tell your healthcare provider about all your medical conditions, including if you:
- have gallbladder problems
- have blood sugar control problems (low blood sugar or high blood sugar)
- have problems with low heart rate
- are pregnant or plan to become pregnant. It is not known if PALSONIFY will harm your unborn baby.
- are breastfeeding or plan to breastfeed. It is not known if PALSONIFY passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby if you take PALSONIFY.
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. PALSONIFY may affect the way other medicines work, and other medicines may affect how PALSONIFY works.
Especially tell your healthcare provider if you take any medicines that can slow the heart rate.
Know the medicines you take. Keep a list of them to show your healthcare provider and pharmacist when you get a new medicine.
What are the possible side effects of PALSONIFY?
PALSONIFY may cause serious side effects including:
- Gallbladder problems: PALSONIFY may cause problems with the gallbladder. Tell your healthcare provider if you have sudden pain in the upper right area of your stomach (abdomen), sudden pain in your right shoulder or between your shoulder blades, yellowing of your skin or the whites of your eyes, or pale stools.
- Blood sugar problems: PALSONIFY may change hormone levels, potentially causing either high blood sugar (hyperglycemia), including diabetes, or low blood sugar (hypoglycemia). Tell your healthcare provider if you have problems with high or low blood sugar. Your healthcare provider will check your blood sugar when you start taking PALSONIFY or when your dose is changed.
- Heart rate problems: Tell your healthcare provider if your heart is not beating normally.
- Thyroid problems: PALSONIFY may keep your thyroid from releasing thyroid hormones, leading to hypothyroidism. Your thyroid function may be checked periodically during your treatment with PALSONIFY.
- Fatty stools: PALSONIFY may cause your body to have problems with absorbing dietary fats. Tell your healthcare provider if you have any new or worsening symptoms, including fatty stools, changes in the color of your stools, loose stools, stomach (abdominal) bloating, or weight loss.
- Low vitamin B12 levels in your blood: Your healthcare provider may check your vitamin B12 levels during treatment with PALSONIFY.
The most common side effects of PALSONIFY include diarrhea, pain in your stomach (abdominal) area, nausea and vomiting, decreased appetite, slow heart rate (bradycardia), high blood sugar levels (hyperglycemia), and irregular heartbeat (palpitations).
These are not all the possible side effects of PALSONIFY. For more information, ask your healthcare provider or pharmacist.
You are encouraged to report negative side effects to Crinetics Pharmaceuticals at 1-833-CRN-INFO (1-833-276-4636) or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
Please see Full Prescribing Information, including Patient Information, and talk to your doctor.
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